Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003268.6

p.L52L

c.154C>T

Surrounding Variants

1 paper

NM_003268.6

p.Y57N

c.169T>A

1 paper

NM_003268.6

p.R59ins1

c.175_176insTAA

1 paper

NM_003268.6

p.T60S

c.178A>T

1 paper

NM_003268.6

p.Q43K

c.127C>A

2 papers

NM_003268.6

p.V61V

c.183C>T

1 paper

NM_003268.6

p.Q40insFs

c.118_119insA

1 paper

NM_003268.6

p.S65S

c.195C>T

1 paper

NM_003268.6

p.N37insFs

c.110_111insC

4 papers

NM_003268.6

p.R34H

c.101G>A

5 papers

NM_003268.6

p.R34C

c.100C>T

2 papers

NM_003268.6

p.Q71*

c.211C>T

1 paper

NM_003268.6

p.I30M

c.90A>G