Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003268.6

p.Q40insFs

c.118_119insA

Surrounding Variants

1 paper

NM_003268.6

p.N37insFs

c.110_111insC

1 paper

NM_003268.6

p.Q43K

c.127C>A

4 papers

NM_003268.6

p.R34H

c.101G>A

5 papers

NM_003268.6

p.R34C

c.100C>T

1 paper

NM_003268.6

p.I30M

c.90A>G

1 paper

NM_003268.6

p.R29Q

c.86G>A

1 paper

NM_003268.6

p.G28V

c.83G>T

1 paper

NM_003268.6

p.L52L

c.154C>T

1 paper

NM_003268.6

p.F26insFs

c.78dupT

1 paper

NM_003268.6

p.Y57N

c.169T>A

1 paper

NM_003268.6

p.P22P

c.66T>G

1 paper

NM_003268.6

p.P22L

c.65C>T