Varaico: Literature-Extracted Genetic Variants

TLR5

350 papers

RefSeq Summary

This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct ...

Pfam Domains

LRR_8aa 81–131UCSCLeucine rich repeat

LRR_8aa 134–182UCSCLeucine rich repeat

LRR_8aa 288–348UCSCLeucine rich repeat

LRR_8aa 320–372UCSCLeucine rich repeat

LRR_8aa 360–415UCSCLeucine rich repeat

LRR_8aa 491–538UCSCLeucine rich repeat

Gene Aliases

HGNC Name

toll like receptor 5

HGNC Previous Symbol

SLEB1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003268.6

p.A15G

c.44C>G

Surrounding Variants

1 paper

NM_003268.6

p.G16C

c.46G>T

1 paper

NM_003268.6

p.L13F

c.37C>T

1 paper

NM_003268.6

p.L9del1

c.25_26delTAG

1 paper

NM_003268.6

p.L8_L9del1

c.24_26delAGG

1 paper

NM_003268.6

p.L8R

c.23T>G

1 paper

NM_003268.6

p.P22L

c.65C>T

1 paper

NM_003268.6

p.P22P

c.66T>G

1 paper

NM_003268.6

p.D6H

c.16G>C

1 paper

NM_003268.6

p.H4H

c.12C>T

1 paper

NM_003268.6

p.F26insFs

c.78dupT

1 paper

NM_003268.6

p.D3V

c.8A>T

1 paper

NM_003268.6

p.G2ins0

c.4_6dupGGA