Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

1–12 of 315 variants

88 papers

NM_006068.5

p.S249P

c.745T>C

12 papers

NM_006068.5

p.I120T

c.359T>C

12 papers

NM_006068.5

p.V427A

c.1280T>C

11 papers

NM_006068.5

p.V327M

c.979G>A

8 papers

NM_006068.5

p.V465I

c.1393G>A

6 papers

NM_006068.5

p.M59T

c.176T>C

6 papers

NM_006068.5

p.L194P

c.581T>C

6 papers

NM_006068.5

p.T361T

c.1083C>G

5 papers

NM_006068.5

p.L199L

c.597T>C

5 papers

NM_006068.5

p.R247K

c.740G>A

5 papers

NM_006068.5

p.K467K

c.1401A>G

5 papers

NM_006068.5

p.A644A

c.1932T>G