Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.R758R

c.2274G>A

Surrounding Variants

3 papers

NM_006068.5

p.T756M

c.2267C>T

1 paper

NM_006068.5

p.K752E

c.2254A>G

1 paper

NM_006068.5

p.W774fs

c.2320_2321fs

1 paper

NM_006068.5

p.N776S

c.2327A>G

1 paper

NM_006068.5

p.P740L

c.2219C>T

1 paper

NM_006068.5

p.I777V

c.2329A>G

1 paper

NM_006068.5

p.P740S

c.2218C>T

1 paper

NM_006068.5

p.A779S

c.2335G>T

1 paper

NM_006068.5

p.A780T

c.2338G>A

1 paper

NM_006068.5

p.M783V

c.2347A>G

1 paper

NM_006068.5

p.I734V

c.2200A>G

1 paper

NM_006068.5

p.L733L

c.2199C>G