Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.L640H

c.1919T>A

Surrounding Variants

1 paper

NM_006068.5

p.H643R

c.1928A>G

1 paper

NM_006068.5

p.H643Q

c.1929T>G

5 papers

NM_006068.5

p.A644A

c.1932T>G

1 paper

NM_006068.5

p.P632H

c.1895C>A

3 papers

NM_006068.5

p.I631R

c.1892T>G

1 paper

NM_006068.5

p.N630S

c.1889A>G

3 papers

NM_006068.5

p.V656V

c.1968G>A

1 paper

NM_006068.5

p.S658R

c.1972A>C

1 paper

NM_006068.5

p.W621*

c.1862G>A

1 paper

NM_006068.5

p.E659G

c.1976A>G

1 paper

NM_006068.5

p.Q620*

c.1858C>T

1 paper

NM_006068.5

p.Q620K

c.1858C>A