Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.W613*

c.1839G>A

Surrounding Variants

1 paper

NM_006068.5

p.L609insFs

c.1826_1827insT

1 paper

NM_006068.5

p.L609L

c.1825T>C

1 paper

NM_006068.5

p.C619C

c.1857C>T

1 paper

NM_006068.5

p.Q620*

c.1858C>T

1 paper

NM_006068.5

p.Q620K

c.1858C>A

1 paper

NM_006068.5

p.W621*

c.1862G>A

4 papers

NM_006068.5

p.V602G

c.1805T>G

1 paper

NM_006068.5

p.A599V

c.1796C>T

1 paper

NM_006068.5

p.V597V

c.1791G>C

1 paper

NM_006068.5

p.V597M

c.1789G>A

1 paper

NM_006068.5

p.N630S

c.1889A>G

3 papers

NM_006068.5

p.I631R

c.1892T>G