Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.I584T

c.1751T>C

Surrounding Variants

1 paper

NM_006068.5

p.N583N

c.1749C>T

1 paper

NM_006068.5

p.N583K

c.1749C>A

1 paper

NM_006068.5

p.T585A

c.1753A>G

2 papers

NM_006068.5

p.L587R

c.1760T>G

1 paper

NM_006068.5

p.I588V

c.1762A>G

1 paper

NM_006068.5

p.I588I

c.1764C>T

1 paper

NM_006068.5

p.S578Y

c.1733C>A

2 papers

NM_006068.5

p.G592V

c.1775G>T

1 paper

NM_006068.5

p.V597M

c.1789G>A

1 paper

NM_006068.5

p.V597V

c.1791G>C

1 paper

NM_006068.5

p.A599V

c.1796C>T

1 paper

NM_006068.5

p.Y567C

c.1700A>G