Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.D557E

c.1671T>G

Surrounding Variants

1 paper

NM_006068.5

p.D557E

c.1671T>A

1 paper

NM_006068.5

p.S558F

c.1673C>T

1 paper

NM_006068.5

p.W555C

c.1665G>T

1 paper

NM_006068.5

p.W555*

c.1665G>A

1 paper

NM_006068.5

p.K560R

c.1679A>G

1 paper

NM_006068.5

p.E565E

c.1695A>G

1 paper

NM_006068.5

p.S566G

c.1696A>G

1 paper

NM_006068.5

p.Y567C

c.1700A>G

1 paper

NM_006068.5

p.I544M

c.1632A>G

1 paper

NM_006068.5

p.S578Y

c.1733C>A

1 paper

NM_006068.5

p.Q532Q

c.1596A>G

1 paper

NM_006068.5

p.Q532H

c.1596A>C