Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.S511L

c.1532C>T

Surrounding Variants

2 papers

NM_006068.5

p.D513N

c.1537G>A

2 papers

NM_006068.5

p.S506S

c.1518A>G

1 paper

NM_006068.5

p.S517R

c.1549A>C

1 paper

NM_006068.5

p.S517N

c.1550G>A

1 paper

NM_006068.5

p.S517R

c.1551C>G

1 paper

NM_006068.5

p.S517R

c.1551C>A

1 paper

NM_006068.5

p.N505H

c.1513A>C

1 paper

NM_006068.5

p.D503Y

c.1507G>T

1 paper

NM_006068.5

p.K520E

c.1558A>G

1 paper

NM_006068.5

p.R522T

c.1565G>C

1 paper

NM_006068.5

p.R522K

c.1565G>A

1 paper

NM_006068.5

p.F494I

c.1480T>A