Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_006068.5

p.K467K

c.1401A>G

Surrounding Variants

3 papers

NM_006068.5

p.V470L

c.1408G>T

3 papers

NM_006068.5

p.V470L

c.1408G>C

1 paper

NM_006068.5

p.V465F

c.1393G>T

1 paper

NM_006068.5

p.V465L

c.1393G>C

8 papers

NM_006068.5

p.V465I

c.1393G>A

1 paper

NM_006068.5

p.S464S

c.1392C>T

1 paper

NM_006068.5

p.S464R

c.1392C>A

1 paper

NM_006068.5

p.I462M

c.1386A>G

1 paper

NM_006068.5

p.A474T

c.1420G>A

1 paper

NM_006068.5

p.A474V

c.1421C>T

2 papers

NM_006068.5

p.S459N

c.1376G>A

1 paper

NM_006068.5

p.S459G

c.1375A>G