Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.S443T

c.1327T>A

Surrounding Variants

1 paper

NM_006068.5

p.D442A

c.1325A>C

1 paper

NM_006068.5

p.D442N

c.1324G>A

1 paper

NM_006068.5

p.M439V

c.1315A>G

1 paper

NM_006068.5

p.P450R

c.1349C>G

1 paper

NM_006068.5

p.L455L

c.1365T>C

1 paper

NM_006068.5

p.I430V

c.1288A>G

2 papers

NM_006068.5

p.L457F

c.1369C>T

1 paper

NM_006068.5

p.V427delFs

c.1281delA

1 paper

NM_006068.5

p.E428fs

c.1282_1283fs

12 papers

NM_006068.5

p.V427A

c.1280T>C

1 paper

NM_006068.5

p.S459G

c.1375A>G

2 papers

NM_006068.5

p.S459N

c.1376G>A