Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.L397P

c.1190T>C

Surrounding Variants

1 paper

NM_006068.5

p.G396S

c.1186G>A

4 papers

NM_006068.5

p.T399M

c.1196C>T

1 paper

NM_006068.5

p.K394*

c.1180A>T

1 paper

NM_006068.5

p.K394E

c.1180A>G

1 paper

NM_006068.5

p.P403S

c.1207C>T

1 paper

NM_006068.5

p.K390K

c.1170A>G

1 paper

NM_006068.5

p.V410I

c.1228G>A

2 papers

NM_006068.5

p.I383T

c.1148T>C

1 paper

NM_006068.5

p.S411S

c.1233C>T

1 paper

NM_006068.5

p.E380E

c.1140G>A

1 paper

NM_006068.5

p.E380G

c.1139A>G

1 paper

NM_006068.5

p.E416G

c.1247A>G