Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.P349L

c.1046C>T

Surrounding Variants

1 paper

NM_006068.5

p.L347P

c.1040T>C

1 paper

NM_006068.5

p.P352T

c.1054C>A

2 papers

NM_006068.5

p.H345Y

c.1033C>T

1 paper

NM_006068.5

p.I344M

c.1032A>G

1 paper

NM_006068.5

p.I344T

c.1031T>C

1 paper

NM_006068.5

p.T354I

c.1061C>T

1 paper

NM_006068.5

p.I338V

c.1012A>G

1 paper

NM_006068.5

p.T337T

c.1011C>T

1 paper

NM_006068.5

p.T361S

c.1081A>T

1 paper

NM_006068.5

p.T361S

c.1082C>G

6 papers

NM_006068.5

p.T361T

c.1083C>G

1 paper

NM_006068.5

p.L336F

c.1008A>T