Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.L324S

c.971T>C

Surrounding Variants

1 paper

NM_006068.5

p.L324L

c.972G>A

11 papers

NM_006068.5

p.V327M

c.979G>A

1 paper

NM_006068.5

p.F328Y

c.983T>A

1 paper

NM_006068.5

p.S320T

c.958T>A

1 paper

NM_006068.5

p.E330E

c.990G>A

1 paper

NM_006068.5

p.E330delFs

c.989delT

1 paper

NM_006068.5

p.I333S

c.998T>G

1 paper

NM_006068.5

p.T313M

c.938C>T

1 paper

NM_006068.5

p.I312I

c.936C>T

1 paper

NM_006068.5

p.L336F

c.1008A>T

1 paper

NM_006068.5

p.T337T

c.1011C>T

1 paper

NM_006068.5

p.H311Y

c.931C>T