Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.I283V

c.847A>G

Surrounding Variants

1 paper

NM_006068.5

p.W274L

c.821G>T

2 papers

NM_006068.5

p.L273L

c.819T>C

1 paper

NM_006068.5

p.I292T

c.875T>C

1 paper

NM_006068.5

p.T298I

c.893C>T

2 papers

NM_006068.5

p.Y299C

c.896A>G

1 paper

NM_006068.5

p.C265F

c.794G>T

1 paper

NM_006068.5

p.C265Y

c.794G>A

1 paper

NM_006068.5

p.T302M

c.905C>T

1 paper

NM_006068.5

p.T302T

c.906G>T

2 papers

NM_006068.5

p.K305I

c.914A>T

1 paper

NM_006068.5

p.E260D

c.780A>T

1 paper

NM_006068.5

p.K305T

c.914A>C