Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.F254F

c.762T>C

Surrounding Variants

1 paper

NM_006068.5

p.F254L

c.762T>G

1 paper

NM_006068.5

p.F254L

c.762T>A

1 paper

NM_006068.5

p.F254L

c.760T>C

4 papers

NM_006068.5

p.T255I

c.764C>T

1 paper

NM_006068.5

p.L252L

c.756G>T

2 papers

NM_006068.5

p.L251*

c.752T>G

2 papers

NM_006068.5

p.L251*

c.752T>A

1 paper

NM_006068.5

p.T250delFs

c.750delG

1 paper

NM_006068.5

p.T250del1

c.748_749delGGT

1 paper

NM_006068.5

p.T250T

c.750C>A

88 papers

NM_006068.5

p.S249P

c.745T>C

1 paper

NM_006068.5

p.E260D

c.780A>T