Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006068.5

p.L225L

c.673C>T

Surrounding Variants

1 paper

NM_006068.5

p.L225M

c.673C>A

1 paper

NM_006068.5

p.L225P

c.674T>C

2 papers

NM_006068.5

p.I228_K229insT

c.682_686ins3

1 paper

NM_006068.5

p.T219I

c.656C>T

1 paper

NM_006068.5

p.N231K

c.693T>A

1 paper

NM_006068.5

p.N218S

c.653A>G

1 paper

NM_006068.5

p.C235S

c.703T>A

1 paper

NM_006068.5

p.C235S

c.704G>C

1 paper

NM_006068.5

p.C235Y

c.704G>A

1 paper

NM_006068.5

p.Q236L

c.707A>T

1 paper

NM_006068.5

p.V213M

c.637G>A

1 paper

NM_006068.5

p.I211V

c.631A>G