Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.A210T

c.628G>A

Surrounding Variants

1 paper

NM_006068.5

p.A210G

c.629C>G

1 paper

NM_006068.5

p.I211V

c.631A>G

1 paper

NM_006068.5

p.V213M

c.637G>A

1 paper

NM_006068.5

p.S207G

c.619A>G

1 paper

NM_006068.5

p.T206I

c.617C>T

1 paper

NM_006068.5

p.T206A

c.616A>G

1 paper

NM_006068.5

p.N218S

c.653A>G

1 paper

NM_006068.5

p.T219I

c.656C>T

5 papers

NM_006068.5

p.L199L

c.597T>C

1 paper

NM_006068.5

p.L199P

c.596T>C

1 paper

NM_006068.5

p.T198delFs

c.593delG

1 paper

NM_006068.5

p.L199F

c.595C>T