Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_006068.5

p.L194P

c.581T>C

Surrounding Variants

1 paper

NM_006068.5

p.I193N

c.578T>A

1 paper

NM_006068.5

p.Q192R

c.575A>G

1 paper

NM_006068.5

p.L191V

c.571C>G

1 paper

NM_006068.5

p.L191I

c.571C>A

2 papers

NM_006068.5

p.T198P

c.592A>C

1 paper

NM_006068.5

p.T198I

c.593C>T

1 paper

NM_006068.5

p.L199F

c.595C>T

1 paper

NM_006068.5

p.L199P

c.596T>C

1 paper

NM_006068.5

p.T198delFs

c.593delG

5 papers

NM_006068.5

p.L199L

c.597T>C

1 paper

NM_006068.5

p.T188K

c.563C>A

1 paper

NM_006068.5

p.T188A

c.562A>G