Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.I166F

c.496A>T

Surrounding Variants

1 paper

NM_006068.5

p.L175L

c.525T>C

1 paper

NM_006068.5

p.L176M

c.526C>A

1 paper

NM_006068.5

p.M156V

c.466A>G

1 paper

NM_006068.5

p.A155A

c.465T>C

1 paper

NM_006068.5

p.R179S

c.537A>C

1 paper

NM_006068.5

p.F150F

c.450C>T

1 paper

NM_006068.5

p.Y182C

c.545A>G

1 paper

NM_006068.5

p.Q147P

c.440A>C

1 paper

NM_006068.5

p.E185E

c.555A>G

1 paper

NM_006068.5

p.S146P

c.436T>C

1 paper

NM_006068.5

p.N144N

c.432C>T

1 paper

NM_006068.5

p.E187V

c.560A>T