Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.I138V

c.412A>G

Surrounding Variants

1 paper

NM_006068.5

p.I138I

c.414C>T

1 paper

NM_006068.5

p.N144N

c.432C>T

1 paper

NM_006068.5

p.S146P

c.436T>C

1 paper

NM_006068.5

p.S129A

c.385T>G

1 paper

NM_006068.5

p.Q147P

c.440A>C

4 papers

NM_006068.5

p.L128V

c.382C>G

1 paper

NM_006068.5

p.D127D

c.381T>C

1 paper

NM_006068.5

p.L126S

c.377T>C

1 paper

NM_006068.5

p.F150F

c.450C>T

1 paper

NM_006068.5

p.R124G

c.370A>G

12 papers

NM_006068.5

p.I120T

c.359T>C

1 paper

NM_006068.5

p.A155A

c.465T>C