Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.Q113P

c.338A>C

Surrounding Variants

1 paper

NM_006068.5

p.Q113L

c.338A>T

1 paper

NM_006068.5

p.Q113*

c.337C>T

1 paper

NM_006068.5

p.K114M

c.341A>T

1 paper

NM_006068.5

p.S116P

c.346T>C

2 papers

NM_006068.5

p.H118Y

c.352C>T

1 paper

NM_006068.5

p.H118D

c.352C>G

1 paper

NM_006068.5

p.H118R

c.353A>G

1 paper

NM_006068.5

p.H118Q

c.354T>G

1 paper

NM_006068.5

p.H118Q

c.354T>A

12 papers

NM_006068.5

p.I120T

c.359T>C

1 paper

NM_006068.5

p.D106A

c.317A>C

1 paper

NM_006068.5

p.L105W

c.314T>G