Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_006068.5

p.S76_E77insFs

c.228_229insT

Surrounding Variants

1 paper

NM_006068.5

p.E77*

c.229G>T

1 paper

NM_006068.5

p.L83L

c.249T>C

1 paper

NM_006068.5

p.V69F

c.205G>T

1 paper

NM_006068.5

p.V69I

c.205G>A

1 paper

NM_006068.5

p.N86Y

c.256A>T

1 paper

NM_006068.5

p.N86D

c.256A>G

1 paper

NM_006068.5

p.R87K

c.260G>A

1 paper

NM_006068.5

p.I88S

c.263T>G

2 papers

NM_006068.5

p.A65T

c.193G>A

1 paper

NM_006068.5

p.I64I

c.192C>A

1 paper

NM_006068.5

p.S60S

c.180T>A

6 papers

NM_006068.5

p.M59T

c.176T>C