Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.L43R

c.128T>G

Surrounding Variants

1 paper

NM_006068.5

p.L43F

c.127C>T

1 paper

NM_006068.5

p.H45D

c.133C>G

1 paper

NM_006068.5

p.K40N

c.120A>T

1 paper

NM_006068.5

p.K40N

c.120A>C

1 paper

NM_006068.5

p.K48E

c.142A>G

1 paper

NM_006068.5

p.D37D

c.111C>T

1 paper

NM_006068.5

p.D37E

c.111C>A

1 paper

NM_006068.5

p.D49D

c.147C>T

1 paper

NM_006068.5

p.L50L

c.150A>G

1 paper

NM_006068.5

p.A35T

c.103G>A

1 paper

NM_006068.5

p.L52L

c.154C>T

1 paper

NM_006068.5

p.F34S

c.101T>C