Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.F34S

c.101T>C

Surrounding Variants

1 paper

NM_006068.5

p.A35T

c.103G>A

1 paper

NM_006068.5

p.E33Q

c.97G>C

1 paper

NM_006068.5

p.G31R

c.91G>C

1 paper

NM_006068.5

p.G31R

c.91G>A

1 paper

NM_006068.5

p.D37D

c.111C>T

1 paper

NM_006068.5

p.D37E

c.111C>A

1 paper

NM_006068.5

p.D30V

c.89A>T

1 paper

NM_006068.5

p.D30G

c.89A>G

2 papers

NM_006068.5

p.D30N

c.88G>A

1 paper

NM_006068.5

p.F28V

c.82T>G

1 paper

NM_006068.5

p.K40N

c.120A>T

1 paper

NM_006068.5

p.K40N

c.120A>C