Varaico: Literature-Extracted Genetic Variants

TLR6

281 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 76–133UCSCLeucine rich repeat

LRR_8aa 450–507UCSCLeucine rich repeat

LRRCTaa 558–583UCSCLeucine rich repeat C-terminal domain

TIRaa 641–796UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 6

HGNC Alias Symbol

CD286

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_006068.5

p.V9L

c.25G>C

Surrounding Variants

1 paper

NM_006068.5

p.S11N

c.32G>A

1 paper

NM_006068.5

p.S11S

c.33C>T

1 paper

NM_006068.5

p.F12I

c.34T>A

1 paper

NM_006068.5

p.F14S

c.41T>C

1 paper

NM_006068.5

p.V15G

c.44T>G

1 paper

NM_006068.5

p.V15A

c.44T>C

1 paper

NM_006068.5

p.V15V

c.45T>C

1 paper

NM_006068.5

p.T2I

c.5C>T

1 paper

NM_006068.5

p.C16R

c.46T>C

1 paper

NM_006068.5

p.V15delFs

c.44delA

1 paper

NM_006068.5

p.M1delFs

c.2delA

3 papers

NM_006068.5

p.M1V

c.1A>G