Varaico: Literature-Extracted Genetic Variants

Gene:TLR7
Variant:p.D332G

TLR7

384 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 496–554UCSCLeucine rich repeat
LRR_1aa 700–721UCSCLeucine Rich Repeat
TIRaa 890–1044UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 7

HGNC Previous Name

toll-like receptor 7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_016562.4
p.D332G
c.995A>G
Surrounding Variants
1 paper
NM_016562.4
p.I330T
c.989T>C
2 papers
NM_016562.4
p.E329G
c.986A>G
1 paper
NM_016562.4
p.E329V
c.986A>T
1 paper
NM_016562.4
p.E329Q
c.985G>C
1 paper
NM_016562.4
p.K328E
c.982A>G
1 paper
NM_016562.4
p.L326L
c.976T>C
1 paper
NM_016562.4
p.S341_L342delFs
c.1021_1025del5
3 papers
NM_016562.4
p.Q344H
c.1032A>T
1 paper
NM_016562.4
p.L345L
c.1035G>A
1 paper
NM_016562.4
p.N314S
c.941A>G
1 paper
NM_016562.4
p.N314D
c.940A>G
1 paper
NM_016562.4
p.L353P
c.1058T>C
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