Varaico: Literature-Extracted Genetic Variants

Gene:TLR7
Variant:p.L1007insFs

TLR7

384 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 496–554UCSCLeucine rich repeat
LRR_1aa 700–721UCSCLeucine Rich Repeat
TIRaa 890–1044UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 7

HGNC Previous Name

toll-like receptor 7

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_016562.4
p.L1007insFs
c.3020_3021insC
Surrounding Variants
1 paper
NM_016562.4
p.L1007fs
c.3019_3020fs
1 paper
NM_016562.4
p.K1005E
c.3013A>G
1 paper
NM_016562.4
p.R1004W
c.3010C>T
1 paper
NM_016562.4
p.Q996E
c.2986C>G
1 paper
NM_016562.4
p.P1019L
c.3056C>T
1 paper
NM_016562.4
p.A1021_F1025del5
c.3061_3074del15
1 paper
NM_016562.4
p.A1021_F1025delFs
c.3062_3075del14
1 paper
NM_016562.4
p.L991I
c.2971C>A
1 paper
NM_016562.4
p.L991F
c.2971C>T
1 paper
NM_016562.4
p.Y1024D
c.3070T>G
5 papers
NM_016562.4
p.L988S
c.2963T>C
2 papers
NM_016562.4
p.L1029L
c.3087A>G
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