Varaico: Literature-Extracted Genetic Variants

TLR8

232 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 276–323UCSCLeucine rich repeat

LRR_8aa 639–700UCSCLeucine rich repeat

LRR_8aa 712–774UCSCLeucine rich repeat

TIRaa 879–1039UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 8

HGNC Alias Symbols

CD288; hTLR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

58 papers

NM_138636.5

p.M1V

c.1A>G

Surrounding Variants

1 paper

NM_138636.5

p.M1delFs

c.2delT

1 paper

NM_138636.5

p.M1delFs

c.1delA

1 paper

NM_138636.5

p.M1I

c.3G>A

2 papers

NM_016610.4

p.M1V

c.1A>G

1 paper

NM_016610.4

p.K18E

c.52A>G