Varaico: Literature-Extracted Genetic Variants

TLR8

232 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved ...

Pfam Domains

LRR_8aa 276–323UCSCLeucine rich repeat

LRR_8aa 639–700UCSCLeucine rich repeat

LRR_8aa 712–774UCSCLeucine rich repeat

TIRaa 879–1039UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 8

HGNC Alias Symbols

CD288; hTLR8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_138636.5

p.N3H

c.7A>C

Surrounding Variants

1 paper

NM_138636.5

p.E2E

c.6A>G

2 papers

NM_138636.5

p.N3I

c.8A>T

1 paper

NM_138636.5

p.M4V

c.10A>G

1 paper

NM_138636.5

p.E2ins0

c.4_6dupGAA

1 paper

NM_138636.5

p.Q7L

c.20A>T

1 paper

NM_138636.5

p.S8L

c.23C>T

1 paper

NM_138636.5

p.S9S

c.27A>C

8 papers

NM_138636.5

p.M10V

c.28A>G

1 paper

NM_138636.5

p.L11L

c.33G>C

1 paper

NM_138636.5

p.L11L

c.33G>T

1 paper

NM_138636.5

p.C13R

c.37T>C

1 paper

NM_138636.5

p.C13G

c.37T>G