Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

18 papers

NM_017442.4

p.S950G

c.2848A>G

Surrounding Variants

1 paper

NM_017442.4

p.S950R

c.2848A>C

2 papers

NM_017442.4

p.S950N

c.2849G>A

1 paper

NM_017442.4

p.F951S

c.2852T>C

1 paper

NM_017442.4

p.R942W

c.2824C>T

1 paper

NM_017442.4

p.E960*

c.2878G>T

2 papers

NM_017442.4

p.R962C

c.2884C>T

1 paper

NM_017442.4

p.R962H

c.2885G>A

1 paper

NM_017442.4

p.K963K

c.2889G>A

1 paper

NM_017442.4

p.D964D

c.2892C>T

1 paper

NM_017442.4

p.V965I

c.2893G>A

2 papers

NM_017442.4

p.T933M

c.2798C>T

1 paper

NM_017442.4

p.V967V

c.2901G>C