Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.Y888*

c.2664C>A

Surrounding Variants

1 paper

NM_017442.4

p.Y888*

c.2664C>G

2 papers

NM_017442.4

p.Y888F

c.2663A>T

1 paper

NM_017442.4

p.N889N

c.2667C>T

2 papers

NM_017442.4

p.R892W

c.2674C>T

3 papers

NM_017442.4

p.A882T

c.2644G>A

1 paper

NM_017442.4

p.C898*

c.2694C>A

1 paper

NM_017442.4

p.F876L

c.2628C>G

1 paper

NM_017442.4

p.F876L

c.2628C>A

1 paper

NM_017442.4

p.F876L

c.2626T>C

2 papers

NM_017442.4

p.R901H

c.2702G>A

1 paper

NM_017442.4

p.W902*

c.2705G>A

1 paper

NM_017442.4

p.W902*

c.2706G>A