Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.L838I

c.2512C>A

Surrounding Variants

2 papers

NM_017442.4

p.L838L

c.2514C>T

1 paper

NM_017442.4

p.G840C

c.2518G>T

1 paper

NM_017442.4

p.W841*

c.2522G>A

1 paper

NM_017442.4

p.W841*

c.2523G>A

1 paper

NM_017442.4

p.L830L

c.2490G>C

1 paper

NM_017442.4

p.L828L

c.2484G>A

2 papers

NM_017442.4

p.S822P

c.2464T>C

2 papers

NM_017442.4

p.A820T

c.2458G>A

1 paper

NM_017442.4

p.Q860R

c.2579A>G

2 papers

NM_017442.4

p.G862E

c.2585G>A

8 papers

NM_017442.4

p.R863Q

c.2588G>A

1 paper

NM_017442.4

p.D864N

c.2590G>A