Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.D634A

c.1901A>C

Surrounding Variants

2 papers

NM_017442.4

p.G629S

c.1885G>A

1 paper

NM_017442.4

p.H641D

c.1921C>G

1 paper

NM_017442.4

p.H641Q

c.1923C>A

1 paper

NM_017442.4

p.G626S

c.1876G>A

1 paper

NM_017442.4

p.P645T

c.1933C>A

1 paper

NM_017442.4

p.R649S

c.1945C>A

1 paper

NM_017442.4

p.R649H

c.1946G>A

1 paper

NM_017442.4

p.E616*

c.1846G>T

1 paper

NM_017442.4

p.Y664Y

c.1992C>T

1 paper

NM_017442.4

p.L603M

c.1807C>A

1 paper

NM_017442.4

p.F667L

c.1999T>C

1 paper

NM_017442.4

p.F667L

c.2001C>G