Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_017442.4

p.P450P

c.1350T>C

Surrounding Variants

1 paper

NM_017442.4

p.P450S

c.1348C>T

1 paper

NM_017442.4

p.D452E

c.1356C>G

1 paper

NM_017442.4

p.D452E

c.1356C>A

1 paper

NM_017442.4

p.W447*

c.1340G>A

1 paper

NM_017442.4

p.P455S

c.1363C>T

1 paper

NM_017442.4

p.P455P

c.1365G>A

1 paper

NM_017442.4

p.P457S

c.1369C>T

2 papers

NM_017442.4

p.D459D

c.1377C>T

1 paper

NM_017442.4

p.T434I

c.1301C>T

1 paper

NM_017442.4

p.R467R

c.1401G>A

1 paper

NM_017442.4

p.C470Y

c.1409G>A

1 paper

NM_017442.4

p.S480P

c.1438T>C