Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.G373S

c.1117G>A

Surrounding Variants

1 paper

NM_017442.4

p.D370D

c.1110C>T

1 paper

NM_017442.4

p.R377H

c.1130G>A

1 paper

NM_017442.4

p.S378P

c.1132T>C

1 paper

NM_017442.4

p.D380N

c.1138G>A

1 paper

NM_017442.4

p.A365T

c.1093G>A

1 paper

NM_017442.4

p.E381G

c.1142A>G

1 paper

NM_017442.4

p.P358_L363delFs

c.1072_1087del16

3 papers

NM_017442.4

p.T383T

c.1149G>A

1 paper

NM_017442.4

p.R385W

c.1153C>T

1 paper

NM_017442.4

p.P358fs

c.1072_1073fs

1 paper

NM_017442.4

p.S355F

c.1064C>T

19 papers

NM_017442.4

p.M392V

c.1174A>G