Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.V290A

c.869T>C

Surrounding Variants

3 papers

NM_017442.4

p.K292*

c.874A>T

1 paper

NM_017442.4

p.R285C

c.853C>T

1 paper

NM_017442.4

p.L283P

c.848T>C

1 paper

NM_017442.4

p.L283L

c.847C>T

1 paper

NM_017442.4

p.F304V

c.910T>G

1 paper

NM_017442.4

p.P273P

c.819C>T

1 paper

NM_017442.4

p.R311*

c.931C>T

1 paper

NM_017442.4

p.R311Q

c.932G>A

1 paper

NM_017442.4

p.V312V

c.936G>C

1 paper

NM_017442.4

p.E267E

c.801G>A

1 paper

NM_017442.4

p.C265F

c.794G>T

1 paper

NM_017442.4

p.C265Y

c.794G>A