Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_017442.4

p.G199G

c.597C>T

Surrounding Variants

1 paper

NM_017442.4

p.G199D

c.596G>A

3 papers

NM_017442.4

p.L198M

c.592C>A

1 paper

NM_017442.4

p.H203N

c.607C>A

1 paper

NM_017442.4

p.H203H

c.609C>T

1 paper

NM_017442.4

p.L204L

c.612G>C

1 paper

NM_017442.4

p.G193S

c.577G>A

1 paper

NM_017442.4

p.A191D

c.572C>A

1 paper

NM_017442.4

p.V190G

c.569T>G

1 paper

NM_017442.4

p.E189E

c.567G>A

1 paper

NM_017442.4

p.L211V

c.631C>G

1 paper

NM_017442.4

p.L188V

c.562C>G

1 paper

NM_017442.4

p.N210_L211del1

c.630_632delAGG