Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.F119S

c.356T>C

Surrounding Variants

1 paper

NM_017442.4

p.A121S

c.361G>T

1 paper

NM_017442.4

p.P123S

c.367C>T

1 paper

NM_017442.4

p.E115K

c.343G>A

1 paper

NM_017442.4

p.I114I

c.342C>T

1 paper

NM_017442.4

p.I114V

c.340A>G

1 paper

NM_017442.4

p.L125V

c.373C>G

1 paper

NM_017442.4

p.E127K

c.379G>A

1 paper

NM_017442.4

p.C110S

c.329G>C

1 paper

NM_017442.4

p.C110S

c.328T>A

1 paper

NM_017442.4

p.P109L

c.326C>T

2 papers

NM_017442.4

p.P109A

c.325C>G

1 paper

NM_017442.4

p.P105P

c.315C>T