Varaico: Literature-Extracted Genetic Variants

TLR9

557 papers

RefSeq Summary

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved...

Pfam Domains

LRR_8aa 51–98UCSCLeucine rich repeat

LRR_8aa 285–345UCSCLeucine rich repeat

LRR_12aa 393–422UCSCLeucine-rich repeat

LRR_8aa 701–762UCSCLeucine rich repeat

TIRaa 870–1026UCSCTIR domain

Gene Aliases

HGNC Name

toll like receptor 9

HGNC Alias Symbol

CD289

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_017442.4

p.G27S

c.79G>A

Surrounding Variants

1 paper

NM_017442.4

p.T23delFs

c.68delG

1 paper

NM_017442.4

p.L24L

c.70C>T

1 paper

NM_017442.4

p.F32S

c.95T>C

1 paper

NM_017442.4

p.P34S

c.100C>T

1 paper

NM_017442.4

p.P34P

c.102C>T

1 paper

NM_017442.4

p.I18T

c.53T>C

1 paper

NM_017442.4

p.H40H

c.120C>T

1 paper

NM_017442.4

p.L11L

c.31C>T

2 papers

NM_017442.4

p.V43V

c.129G>C

1 paper

NM_017442.4

p.P10S

c.28C>T

1 paper

NM_017442.4

p.N46T

c.137A>C

3 papers

NM_017442.4

p.R5C

c.13C>T