Varaico: Literature-Extracted Genetic Variants

Gene:TNF
Variant:p.R8R

TNF

4,267 papers

RefSeq Summary

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus func...

Pfam Domains

TNFaa 102–233UCSCTNF(Tumour Necrosis Factor) family

Gene Aliases

HGNC Name

tumor necrosis factor

HGNC Previous Symbol

TNFA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000594.4
p.R8R
c.24G>T
Surrounding Variants
3 papers
NM_000594.4
p.R8R
c.24G>A
5 papers
NM_000594.4
p.D9N
c.25G>A
1 paper
NM_000594.4
p.R8Q
c.23G>A
13 papers
NM_000594.4
p.D9H
c.25G>C
2 papers
NM_000594.4
p.D9A
c.26A>C
1 paper
NM_000594.4
p.D9G
c.26A>G
1 paper
NM_000594.4
p.R8R
c.22C>A
1 paper
NM_000594.4
p.R8insFs
c.23dupG
2 papers
NM_000594.4
p.R8G
c.22C>G
2 papers
NM_000594.4
p.R8W
c.22C>T
2 papers
NM_000594.4
p.I7I
c.21C>A
1 paper
NM_000594.4
p.D9E
c.27C>A
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