Varaico: Literature-Extracted Genetic Variants

TNFRSF10A

348 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces...

Pfam Domains

TNFR_c6aa 148–188UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 190–229UCSCTNFR/NGFR cysteine-rich region

Deathaa 366–448UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10a

HGNC Alias Symbols

DR4; Apo2; TRAILR-1; CD261; TRAILR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003844.4

p.A399V

c.1196C>T

Surrounding Variants

1 paper

NM_003844.4

p.D395N

c.1183G>A

1 paper

NM_003844.4

p.M411T

c.1232T>C

1 paper

NM_003844.4

p.L383F

c.1147C>T

1 paper

NM_003844.4

p.R421W

c.1261C>T

1 paper

NM_003844.4

p.R421L

c.1262G>T

1 paper

NM_003844.4

p.V375L

c.1123G>C

1 paper

NM_003844.4

p.L428R

c.1283T>G

1 paper

NM_003844.4

p.L364_M365insG

c.1090_1094ins3

1 paper

NM_003844.4

p.R438G

c.1312A>G

9 papers

NM_003844.4

p.R441K

c.1322G>A

1 paper

NM_003844.4

p.T461A

c.1381A>G

2 papers

NM_003844.4

p.*469L

c.1406G>T