Varaico: Literature-Extracted Genetic Variants

TNFRSF10A

348 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces...

Pfam Domains

TNFR_c6aa 148–188UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 190–229UCSCTNFR/NGFR cysteine-rich region

Deathaa 366–448UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10a

HGNC Alias Symbols

DR4; Apo2; TRAILR-1; CD261; TRAILR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003844.4

p.Q318*

c.952C>T

Surrounding Variants

1 paper

NM_003844.4

p.Q318H

c.954G>C

1 paper

NM_003844.4

p.T308T

c.924T>C

1 paper

NM_003844.4

p.L323_T327delFs

c.967_979del13

1 paper

NM_003844.4

p.Q329R

c.986A>G

1 paper

NM_003844.4

p.S330F

c.989C>T

1 paper

NM_003844.4

p.S330delins

c.989_990delinsTT

1 paper

NM_003844.4

p.L300P

c.899T>C

1 paper

NM_003844.4

p.C336Y

c.1007G>A

1 paper

NM_003844.4

p.E298D

c.894G>T

1 paper

NM_003844.4

p.E298D

c.894G>C

1 paper

NM_003844.4

p.E298V

c.893A>T

1 paper

NM_003844.4

p.N297S

c.890A>G