Varaico: Literature-Extracted Genetic Variants

TNFRSF10A

348 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces...

Pfam Domains

TNFR_c6aa 148–188UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 190–229UCSCTNFR/NGFR cysteine-rich region

Deathaa 366–448UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10a

HGNC Alias Symbols

DR4; Apo2; TRAILR-1; CD261; TRAILR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_003844.4

p.R282S

c.844C>A

Surrounding Variants

1 paper

NM_003844.4

p.R282C

c.844C>T

1 paper

NM_003844.4

p.R282G

c.844C>G

1 paper

NM_003844.4

p.L285I

c.853C>A

1 paper

NM_003844.4

p.V278A

c.833T>C

1 paper

NM_003844.4

p.G288E

c.863G>A

1 paper

NM_003844.4

p.P289R

c.866C>G

1 paper

NM_003844.4

p.G290R

c.868G>C

1 paper

NM_003844.4

p.G290R

c.868G>A

1 paper

NM_003844.4

p.E292K

c.874G>A

1 paper

NM_003844.4

p.E292G

c.875A>G

1 paper

NM_003844.4

p.N297H

c.889A>C

1 paper

NM_003844.4

p.N297S

c.890A>G