Varaico: Literature-Extracted Genetic Variants

TNFRSF10A

348 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces...

Pfam Domains

TNFR_c6aa 148–188UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 190–229UCSCTNFR/NGFR cysteine-rich region

Deathaa 366–448UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10a

HGNC Alias Symbols

DR4; Apo2; TRAILR-1; CD261; TRAILR1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003844.4

p.R52R

c.154C>A

Surrounding Variants

1 paper

NM_003844.4

p.R52Q

c.155G>A

2 papers

NM_003844.4

p.A54V

c.161C>T

1 paper

NM_003844.4

p.G49D

c.146G>A

1 paper

NM_003844.4

p.P56T

c.166C>A

1 paper

NM_003844.4

p.M59I

c.177G>T

1 paper

NM_003844.4

p.R44M

c.131G>T

1 paper

NM_003844.4

p.M59I

c.177G>C

1 paper

NM_003844.4

p.M59I

c.177G>A

1 paper

NM_003844.4

p.G60E

c.179G>A

2 papers

NM_003844.4

p.G39D

c.116G>A

1 paper

NM_003844.4

p.S65T

c.194G>C

1 paper

NM_003844.4

p.V37E

c.110T>A