Varaico: Literature-Extracted Genetic Variants

TNFRSF10B

211 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis indu...

Pfam Domains

TNFR_c6aa 97–137UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 139–178UCSCTNFR/NGFR cysteine-rich region

Deathaa 339–422UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10b

HGNC Alias Symbols

DR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2

Papers

RefSeq ID

Protein change

DNA change

1–12 of 126 variants

12 papers

NM_003842.5

p.A67V

c.200C>T

7 papers

NM_003842.5

p.D269H

c.805G>C

6 papers

NM_003842.5

p.*441*

c.1322A>G

5 papers

NM_003842.5

p.P32L

c.95C>T

5 papers

NM_003842.5

p.V191A

c.572T>C

4 papers

NM_003842.5

p.G250Splc

c.748+1G>A

2 papers

NM_003842.5

p.M1T

c.2T>C

2 papers

NM_003842.5

p.Y103C

c.308A>G

2 papers

NM_003842.5

p.C129S

c.386G>C

2 papers

NM_003842.5

p.T219T

c.657A>G

2 papers

NM_003842.5

p.A221V

c.662C>T

1 paper

NM_003842.5

p.R4R

c.12G>C