Varaico: Literature-Extracted Genetic Variants

TNFRSF10B

211 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis indu...

Pfam Domains

TNFR_c6aa 97–137UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 139–178UCSCTNFR/NGFR cysteine-rich region

Deathaa 339–422UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10b

HGNC Alias Symbols

DR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_003842.5

p.*441*

c.1322A>G

Surrounding Variants

1 paper

NM_003842.5

p.F428Y

c.1283T>A

1 paper

NM_003842.5

p.I418V

c.1252A>G

1 paper

NM_003842.5

p.K415N

c.1245G>T

1 paper

NM_003842.5

p.K415N

c.1245G>C

1 paper

NM_003842.5

p.L413R

c.1238T>G

1 paper

NM_003842.5

p.E411A

c.1232A>C

1 paper

NM_003842.5

p.A405A

c.1215C>T

1 paper

NM_003842.5

p.A397G

c.1190C>G

1 paper

NM_003842.5

p.R395Q

c.1184G>A

1 paper

NM_003842.5

p.Y383*

c.1149C>G

1 paper

NM_003842.5

p.Y383*

c.1149C>A

1 paper

NM_003842.5

p.A376V

c.1127C>T