Varaico: Literature-Extracted Genetic Variants

TNFRSF10B

211 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis indu...

Pfam Domains

TNFR_c6aa 97–137UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 139–178UCSCTNFR/NGFR cysteine-rich region

Deathaa 339–422UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10b

HGNC Alias Symbols

DR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

7 papers

NM_003842.5

p.D269H

c.805G>C

Surrounding Variants

1 paper

NM_003842.5

p.D269A

c.806A>C

1 paper

NM_003842.5

p.R264*

c.790C>T

1 paper

NM_003842.5

p.P285T

c.853C>A

1 paper

NM_003842.5

p.M289R

c.866T>G

1 paper

NM_003842.5

p.P297S

c.889C>T

1 paper

NM_003842.5

p.P305L

c.914C>T

1 paper

NM_003842.5

p.P255_E256insFs

c.765_766insC

4 papers

NM_003842.5

p.G250Splc

c.748+1G>A

1 paper

NM_003842.5

p.Y243F

c.728A>T

1 paper

NM_003842.5

p.V240insFs

c.718_719ins4

1 paper

NM_003842.5

p.V240A

c.719T>C

1 paper

NM_003842.5

p.K239R

c.716A>G