Varaico: Literature-Extracted Genetic Variants

TNFRSF10B

211 papers

RefSeq Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis indu...

Pfam Domains

TNFR_c6aa 97–137UCSCTNFR/NGFR cysteine-rich region

TNFR_c6aa 139–178UCSCTNFR/NGFR cysteine-rich region

Deathaa 339–422UCSCDeath domain

Gene Aliases

HGNC Name

TNF receptor superfamily member 10b

HGNC Alias Symbols

DR5; KILLER; TRICK2A; TRAIL-R2; TRICKB; CD262; TRAILR2

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_003842.5

p.P208S

c.622C>T

Surrounding Variants

1 paper

NM_003842.5

p.P208L

c.623C>T

1 paper

NM_003842.5

p.C209S

c.626G>C

1 paper

NM_003842.5

p.S200fs

c.598_599fs

1 paper

NM_003842.5

p.S200delFs

c.598delA

2 papers

NM_003842.5

p.T219T

c.657A>G

1 paper

NM_003842.5

p.E195A

c.584A>C

2 papers

NM_003842.5

p.A221V

c.662C>T

1 paper

NM_003842.5

p.A193V

c.578C>T

1 paper

NM_003842.5

p.V223I

c.667G>A

1 paper

NM_003842.5

p.P192P

c.576A>G

1 paper

NM_003842.5

p.V191G

c.572T>G

5 papers

NM_003842.5

p.V191A

c.572T>C